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    • Association of lipid-lowering drugs and antidiabetic drugs with age-related macular degeneration: A meta-analysis in Europeans 

      Mauschitz, Matthias M.; Verzijden, Timo; Schuster, Alexander K.; Elbaz, Hisham; Pfeiffer, Norbert; Khawaja, Anthony; Luben, Robert N.; Foster, Paul J.; Rauscher, Franziska G.; Wirkner, Kerstin; Kirsten, Toralf; Jonas, Jost B.; Bikbov, Mukharram M.; Hogg, Ruth; Peto, Tunde; Cougnard-Grégoire, Audrey; Bertelsen, Geir; Erke, Maja Gran; Topouzis, Fotis; Giannoulis, Dimitrios A.; Brandl, Caroline; Heid, Iris M.; Creuzot-Garcher, Catherine P.; Gabrielle, Pierre-Henry; Hense, Hans-Werner; Pauleikhoff, Daniel; Barreto, Patricia; Coimbra, Rita; Piermarocchi, Stefano; Daien, Vincent; Holz, Frank G.; Delcourt, Cecile; Finger, Robert P. (Journal article; Tidsskriftartikkel, 2022-11-07)
      <p><i>Background/aims</i> To investigate the association of commonly used systemic medications with prevalent age-related macular degeneration (AMD) in the general population. <p><i>Methods</i> We included 38 694 adults from 14 population-based and hospital-based studies from the European Eye Epidemiology consortium. We examined associations between the use of systemic medications and any prevalent ...

    • Associations of inner retinal layers with risk of incident dementia: An individual participant data analysis of four prospective cohort studies 

      van der Heide, Frank C. T.; Khawaja, Anthony; Berendschot, Tos T. J. M.; Littlejohns, Thomas J.; Kuźma, Elżbieta; Luben, Robert; Patel, Praveen J.; Foster, Paul J.; Bertelsen, Geir; von Hanno, Therese; Johnsen, Bente; Schirmer, Henrik; Rebouças, Sara C. L.; Grasset, Leslie; Delcourt, Cécile; Helmer, Catherine; Stehouwer, Coen D. A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-08)
      INTRODUCTION - Our main objective was to investigate whether retinal neurodegeneration, estimated from lower thickness of inner retinal layers, was associated with incident all-cause dementia and Alzheimer's disease (AD).<p> <p>METHODS - We performed an individual participant data meta-analysis using unpublished data from four prospective cohort studies with a total of 69,955 participants (n = ...